Heat Transfer and Granule Growth Rate in Fluidized Bed Granulation.
نویسندگان
چکیده
منابع مشابه
Bed Voidage and Heat Transfer in Non-Newtonian Liquid-Solid Fluidized Bed
The presence of particles in liquid-solid fluidized beds enhances the bed heat transfer, because the movement of the particles leads to an increased turbulence in the system. Moreover, the violent movement of the particles has a positive effect on fouling of the heat transfer surface. The aim of this investigation was to perform systematic measurements of bed voidage and heat transfer coeff...
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Size enlargement of fine powders by wet granulation involves mixing of fine particles with a binder liquid to form larger wet granules and drying them by evaporation of the binder liquid to form larger dry granules. Identification of the time for completion of granulation process is critical as further mixing of dry granules is providing extra energy for their attrition. In a batch fluidized be...
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Here, we statistically identified the critical factor of the granulation rate during the fluidized bed granulation process. Lactose was selected as the excipient and was granulated with several binders, including hydroxypropyl cellulose, hydroxypropyl methyl cellulose, and polyvinylpyrrolidone. The viscosity, density, and surface tension of the binder solution, contact angle, and the work done ...
متن کاملbed voidage and heat transfer in non-newtonian liquid-solid fluidized bed
the presence of particles in liquid-solid fluidized beds enhances the bed heat transfer, because the movement of the particles leads to an increased turbulence in the system. moreover, the violent movement of the particles has a positive effect on fouling of the heat transfer surface. the aim of this investigation was to perform systematic measurements of bed voidage and heat transfer coefficie...
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A model was developed taking into consideration the heat and mass transfer processes in liquidsprayed fluidized beds. Such fluidized beds (FB) are used for granulation, coating and agglomeration. Conclusions are drawn on the relevance of particle dispersion, spraying and drying to temperature and concentrations distributions. In extension, the model was coupled with a population balance model t...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1996
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.44.572